The Lowdown on Transcriptional Reporters
Gene reporter assays have contributed hugely to our understanding of how genes are regulated during growth and development, for example, through the study of spatiotemporal gene expression patterns,...
The Challenges In Small Molecule Drug Development – Part 2: Target Identification
Welcome back to our small molecule drug development series! If you’re only joining us now, check out our introductory article to drug discovery. Otherwise let’s dive straight into the world of drug...
The Challenges In Small Molecule Drug Development – Part I
The world of drug discovery is rife with new approaches within immunotherapy (e.g., T cell-based cancer therapies), personalized vaccines, microbiome therapies, and CRISPR-based therapies in an...
Providing the Right Cues for Organoid Development
Organoids are in vitro-derived miniaturized organs that exhibit self-organization and recapitulate the functions of the in vivo organ they represent. For organoids to mimic their real-life...
Can MSCs Become A New Treatment Option for Cancer?
In addition to their potential for cellular therapy and modeling of developmental processes and disease, mesenchymal cells (MSCs) are rapidly gaining traction in cancer therapy. Although they are...
Cancer Organoids – A New Era in Cancer Treatment
In simple terms, cancer organoids are organoids that are generated from cells donated by cancer patients. In our previous post about organoids, we described their many uses and applications, ranging...
Cellular Therapies and Research Models – the Powers of MSCs
We gave you an introduction to mesenchymal cells (MSCs) in one of our earlier Cell of the Month posts. Staying with the theme of recapitulating in vivo development processes (check out our most...
What’s All the Fuss About Organoids?
In the modern fast-paced worlds of research and medicine, disease models that take us closer to the real-life situation are highly desirable. While we can’t discredit the power of in vitro cell...
Can Genetics Explain Schizophrenia?
In one of our recent posts, we addressed the types of genetic variability that exist in humans and why a greater understanding of these is critical in diagnostics, for predicting our response to new...