The Skinny On Our Largest Organ
A few years ago, I got into a heated debate. The topic was: what is the largest organ in the body? My "opponent", a very bright student studying human health and disease, insisted that the liver was...
Astrocytes: What Are They and What Do They Do?
Q 1 & 2: What Are Astrocytes? What Do Astrocytes Do? Astrocytes or astroglia are the largest and most numerous types of glial cells (see below) in the Central Nervous System (CNS). There are...
Patient-derived Human Xenografts: Their Pros and Cons as Cancer Models
A xenograft (or heterograft) is a piece of living tissue taken from a donor of one species and grafted into a recipient of different species. Cancer refers to a group of diseases characterized by...
Hepatocytes: Driving Drug Discovery
Hepatocytes are widely used to screen potential drug candidates and have allowed researchers to fast-track many new treatments into clinical trials. Quickly releasing new drug treatments that meet...
Microglia: key cells to understanding Alzheimer’s Disease
Microglia have been studied extensively for their role in various neurodegenerative diseases and brain injuries, including Alzheimer’s disease, Parkinson’s disease, Epilepsy, Frontal Temporal...