Cell of the Month: Mast Cells

Mast cells are tissue-resident immune cells derived from the myeloid lineage, and along with basophils, eosinophils and neutrophils, they belong to the granulocyte family of white blood cells.  First discovered and named almost 200 years ago by German pathologist...
Mysteries of the Mighty Melanocytes

Mysteries of the Mighty Melanocytes

Melanocytes are cells that produce melanin, the pigment present in our skin, eyes, and hair. iPS-derived melanocytes are used in models of skin disease, drug toxicity assays, skin bioprinting and in...

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Melanocytes, Melanin, and More

Melanocytes, Melanin, and More

Melanocytes are melanin-producing cells found mainly in the lowest part of the top layer of your skin or to put it in science-speak: the stratum basale of your epidermis (see our article on the...

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The Skinny On Our Largest Organ

The Skinny On Our Largest Organ

A few years ago, I got into a heated debate. The topic was: what is the largest organ in the body? My "opponent", a very bright student studying human health and disease, insisted that the liver was...

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Disease Models