by Karen O'Hanlon Cohrt | Jul 16, 2018 | Trends
The world of drug discovery is rife with new approaches within immunotherapy (e.g., T cell-based cancer therapies), personalized vaccines, microbiome therapies, and CRISPR-based therapies in an attempt to provide novel treatments and cures for a wide range of...
by Karen O'Hanlon Cohrt | Jul 2, 2018 | Trends
Organoids are in vitro-derived miniaturized organs that exhibit self-organization and recapitulate the functions of the in vivo organ they represent. For organoids to mimic their real-life counterparts as much as possible, they must receive appropriate physical and...
by Karen O'Hanlon Cohrt | Jun 18, 2018 | Trends
In addition to their potential for cellular therapy and modeling of developmental processes and disease, mesenchymal cells (MSCs) are rapidly gaining traction in cancer therapy. Although they are not the only stem cells with anti-cancer activity, MSCs are often...
by Karen O'Hanlon Cohrt | May 25, 2018 | Trends
In simple terms, cancer organoids are organoids that are generated from cells donated by cancer patients. In our previous post about organoids, we described their many uses and applications, ranging from disease models, drug and toxicity testing, tissue and organ...
by Karen O'Hanlon Cohrt | May 2, 2018 | Trends
We gave you an introduction to mesenchymal cells (MSCs) in one of our earlier Cell of the Month posts. Staying with the theme of recapitulating in vivo development processes (check out our most recent post on organoids), we wanted to take a closer look at MSCs and...