by Karen O'Hanlon Cohrt | Oct 1, 2018 | Trends
Gene reporter assays have contributed hugely to our understanding of how genes are regulated during growth and development, for example, through the study of spatiotemporal gene expression patterns, as well as how gene expression is regulated by transcription factors,...
by Karen O'Hanlon Cohrt | Sep 10, 2018 | Trends
Welcome back to our small molecule drug development series! If you’re only joining us now, check out our introductory article to drug discovery. Otherwise let’s dive straight into the world of drug target identification! So, What Is a Drug Target? In the world of drug...
by Karen O'Hanlon Cohrt | Aug 16, 2018 | Cell Culture Techniques
The remarkable propensity of mesenchymal stem cells (MSCs) for self-renewal, multi-lineage differentiation and immune-modulatory activity has attracted much attention within the cell therapy area, from their potential in cell therapies and research models to their...
by Karen O'Hanlon Cohrt | Jul 30, 2018 | Disease Models
Cell of The Month: Osteoblasts Osteoblasts, often referred to as bone-forming cells, are specialized and terminally differentiated products of mesenchymal stem cells whose major function is to synthesize bone in a process known as osteogenesis. Osteogenesis During...
by Karen O'Hanlon Cohrt | Jul 16, 2018 | Trends
The world of drug discovery is rife with new approaches within immunotherapy (e.g., T cell-based cancer therapies), personalized vaccines, microbiome therapies, and CRISPR-based therapies in an attempt to provide novel treatments and cures for a wide range of...
