by Karen O'Hanlon Cohrt | Feb 4, 2025 | Cell Culture Techniques, Disease Models
Induced pluripotent stem cells (iPSCs) have become a mainstay in disease modeling and drug development, offering almost unlimited opportunities to study human biology in the lab. However, working with these cells can present hurdles that catch even the most seasoned...
by Karen O'Hanlon Cohrt | Dec 9, 2024 | Disease Models
Welcome back to our Cell of the Month series! This time, we are talking about Kupffer cells – what they are, what they do, and why we should want to learn more about them! Kupffer cells – the gatekeepers of the liver First described by German anatomist...
by Karen O'Hanlon Cohrt | Oct 29, 2024 | Trends
Trogocytosis, from trogo meaning ‘to gnaw’ or ‘to nibble’ in Ancient Greek, is an active process during which one cell receives cell surface molecules and membrane fragments from another cell in a unidirectional and cell-contact dependent manner. Within immune cells,...
by Karen O'Hanlon Cohrt | Sep 24, 2024 | Citation Alerts
Tempo-iOligo™was cited in Nature in a major infectious disease study that offers the first explanation as to why herpes simplex virus 1 (HSV-1) infection in the brain is very rare, despite the fact that most of us have been infected with the virus. The study used...
by Karen O'Hanlon Cohrt | Jul 24, 2024 | Trends
In our last article, we introduced mast cells, their origins and morphology, and summarized how they are activated during IgE-mediated allergic responses. Here, we shift gears and explore how mast cells, together with microglia and the blood brain barrier, contribute...
