Cell-based models for human diseases

Cell-based assay technology reagents

The Forgotten Process – Trogocytosis!

Trogocytosis, from trogo meaning ‘to gnaw’ or ‘to nibble’ in Ancient Greek, is an active process during which one cell receives cell surface molecules and membrane fragments from another cell in a unidirectional and cell-contact dependent manner.  Within immune cells, trogocytosis is triggered by receptor–ligand interactions and can occur within minutes of conjugate formation between two live cells. Although the names sound similar, trogocytosis is distinct from phagocytosis, which involves complete engulfment of one cell by another. An ancient, multifunctional process The term trogocytosis was coined by Denis Hudrisier and Etienne Joly in 2002 (1). However, the first reports of...

Cell of the Month: Mast Cells

Mast cells are tissue-resident immune cells derived from the myeloid lineage, and along with basophils, eosinophils and neutrophils, they belong to the granulocyte family of white blood cells.  First discovered and named almost 200 years ago by German pathologist...

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Cell of the Month: Pericytes

It’s a fibroblast-like cell adorned with long cytoplasmic processes that wrap around the endothelial cells in blood vessels, it controls blood flow through the blood vessels, and it is essential for normal brain function and development. Which cell type is it? Well,...

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Tempo Bioscience Services

Disease Models and Assay Services

Tempo offers services and alliances based on our advanced technological platforms and a range of capabilities. Our team differentiates ourselves based on a strong commitment to innovative solutions and quality R&D for our partners.

Tempo Bioscience Support

On Demand Custom Engineered Cell Models

Tempo develops patient relevant stem cell (iPSCs) based models to support drug discovery, preclinical studies, and early-stage clinical development.