Tempo-iOligo™was cited in Nature in a major infectious disease study that offers the first explanation as to why herpes simplex virus 1 (HSV-1) infection in the brain is very rare, despite the fact that most of us have been infected with the virus. The study used CRISPR screens to find new factors involved in controlling HSV-1 replication in the brain, and found that depletion of the transmembrane protein TMEFF1 in human neurons and in mice led to increased viral replication and neuronal death following HSV-1 infection.  Tempo’s iOligo cells are induced oligodendrocyte progenitors reprogrammed from human skin fibroblasts using Tempo’s proprietary reprogramming technology. While...